Amoxicillin is a bactericidal antibiotic that belongs to semi-synthetic penicillins and has a wide spectrum of action. It is a 4-hydroxyl analog of ampicillin and has a bactericidal effect. It acts destructively on gram-negative and gram-positive cocci, as well as on certain gram-negative rods (Salmonella, E. coli, klebsiella, shigella).
Amoxicillin (Amoxil) does not affect microorganisms that produce penicillinase. It is absorbed in a short time and almost completely dissolves in the intestines. The drug is resistant to an acidic environment. The highest concentration of the drug is observed in the plasma after 1-2 hours. It is mostly excreted through the kidneys, and the half-life is 1.5 hours.
The dosage and duration of treatment is prescribed individually, depending on the severity of the disease and the sensitivity of microorganisms. Amoxicillin capsules are taken orally before or after a meal and then washed down with water. Adults and children over 10 years of age are prescribed a dose of 500 mg 3 times a day.
In case of severe course of the disease – 1 g 3 times a day. Children from 5 to 10 years are prescribed the drug 3 times a day for 0.25 g. The age group of children from 2 to 5 years is prescribed 0.125 g 3 times a day. For children under 2 years of age, the recommended dose is prescribed at the rate of 20 mg per kilogram of body weight up to 3 times a day. In the age group of patients under 10 years of age, Amoxicillin is better prescribed in the form of a suspension. The course of treatment with the drug is 5-12 days long.
For use as monotherapy and in combination with clavulanic acid, infectious and inflammatory diseases caused by sensitive microorganisms are present including:
The drug is indicated for infections of the respiratory system, urinary tract infections, etc. A cold is often accompanied by such conditions as a runny nose, sore throat, sometimes fever and cough. If the symptoms are accompanied by more than 3-5 days, then it is necessary to connect the antibiotic Amoxicillin, the dosage and course of treatment of which is prescribed by the doctor, based on the patient’s age, weight, severity of the pathological process. The standard dosage of Amoxicillin is 500 mg 3 times/day, if the disease is severe, then the dosage is increased by 2 times.
For children under 10 years of age, granules are usually prescribed for the preparation of a suspension for oral administration. The dose and course of treatment are set by the doctor, taking into account the age and body weight of the child, as well as the severity of the disease. The daily dose of Amoxicillin for children, depending on the indications and the clinical situation, can be 20-100 mg/kg in 2-3 doses. If the disease is accompanied by an elevated temperature, then doctors additionally prescribe antipyretic drugs (e.g., non-steroidal anti-inflammatory drugs).
An antibiotic is prescribed by doctors for gum inflammation. Toothache usually occurs when the mucous membrane around the gum is swollen. It can cause the development of a flux — a purulent disease in the subgingival and subcostal jaw area. The course of treatment and dosage is set by the attending physician! Most often, the duration of treatment is 7 days.
It is not recommended to prescribe this drug in conjunction with bacteriostatically acting antimicrobial drugs. With simultaneous administration of Amoxicillin and oral contraceptives, the effectiveness of the latter may decrease. An allergic reaction in the form of rashes is possible when taken simultaneously with allopurinol.